In vivo experiments display anatomically selective neurochemical effects of modafinil on monoaminergic systems (de Saint Hilaire et al 2001; Ferraro et al 2002), and, notably, even though modafinil raises TMN fos expression (Scammell et al 2000) and HAergic tone it's unable to exert this effect

THC has psychoactive Attributes and binds to cannabinoid receptors, leading to the attribute “superior” associated with cannabis use. CBD, Alternatively, won't develop psychoactive consequences but can impact the ECS in various ways, potentially providing therapeutic Advantages.